CMA 120 System for Freely Moving Animals

The CMA 120 System for Freely Moving Animals enables microdialysis studies on conscious, small laboratory animals over long periods of time.



  • Balance arm with dual channel swivel

  • Secures tubing away from the animal and prevents twisting

Ordering Information

Availability: In stock

Product Name Item # Price
CMA 120 System for Freely Moving Animals 8309049 View Price
CMA 120 Bowl with Food and Water Containers (Height 360 mm, Diameter 400 mm) 8309672 View Price
CMA 120 System without Bowl 8409029 View Price
CMA 120 Plastic Bowl (Height 360 mm, Diameter 400 mm) 8309031 View Price
CMA 120 Complete Swivel Assembly 8309048 View Price
CMA 120 Swivel Assembly without Swivel 2409090 View Price
CMA 120 Wire Set with Collar Connector 2409051 View Price
CMA 120 Balance Arm 8309032 View Price
CMA 120 Swivel Pin and Gimbal 8002714 View Price
CMA 120 Plastic Vial Holder 2409069 View Price
CMA 120 Wire Attachment 2409091 View Price
Clamp for CMA 120 Vial Holder 8409033 View Price
Plastic Animal Collar (pkg. of 100) 7431059 View Price
Tubing Adapters for CMA Microdialysis Probes, pkg. of 10 3409500 View Price
FEP Tubing, 0.12 mm ID, 1 m, pkg. of 1 3409501 View Price
FEP Tubing, 0.12 mm ID, 1 m, pkg. of 10 8409501 View Price
CMA 120 Instrument Table 8309046 View Price
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Description
Details

The CMA 120 System for Freely Moving Animals enables microdialysis studies on conscious, small laboratory animals over long periods of time.

CMA 120 System for Freely Moving Animals includes:

  • CMA 120 plastic bowl
  • CMA 120 swivel assembly
  • CMA 120 balance arm
  • Plastic collar (100 pcs)
  • Tubing adapters (10 pcs)
  • FEP tubing (1 m)
  • Vial, plastic 300 μl (25 pcs)
  • Caps, plastic (25 pcs)

The CMA 120 instrument can be used in combination with any one of the microdialysis systems. The microdialysis probe is attached to a CMA Syringe Pump, the CMA 110 Liquid Switch, and to any of the CMA 142 or CMA 470 collection devices via a dual channel swivel.

The swivel is mounted on the balancing arm allowing free movement of the animal. The swivel brace holds a wire with a collar connector and two holders for 300 µl plastic vials.

The wire attached to the animal collar turns the swivel and supports the tubing. Manual fraction collection is used when two microdialysis probes are implanted, or when microdialysis is combined with local injection via one channel of the swivel.

The CMA 120 Bowl with Food and Water Containers is used in studies where a freely moving animal will be contained for longer periods of time. The additions of these containers allow the animal to feed and drink ad libitum. The food container and water bottle are arranged on the outside of the bowl so as not to disturb the movement of the tethered animal when inside the bowl.

Both containers are easily removed for cleaning and refilling.

Journal Articles

Recent Selected Publications

 

Paasonen, J. et al., 2017. Dose-response effect of acute phencyclidine on functional connectivity and dopamine levels, and their association with schizophrenia-like symptom classes in rat. Neuropharmacology, 119, pp.15–25.

 

Jin, W.-S. et al., 2017. Peritoneal dialysis reduces amyloid-beta plasma levels in humans and attenuates Alzheimer-associated phenotypes in an APP/PS1 mouse model. Acta Neuropathologica, pp.1–14.

 

Bank, J.H.H. et al., 2017. Gene expression analysis and microdialysis suggest hypothalamic triiodothyronine (T3) gates daily torpor in Djungarian hamsters (Phodopus sungorus). Journal of Comparative Physiology B, pp.1–12.

 

Xiao, B.-X. et al., 2016. Pharmacokinetic profiles of the five isoflavonoids from Pueraria lobata roots in the CSF and plasma of rats. Journal of Ethnopharmacology, 184, pp.22–29.

 

Lindqvist, A. et al., 2016. In vivo Functional Evaluation of Increased Brain Delivery of the Opioid Peptide DAMGO by Glutathione-PEGylated Liposomes. Pharmaceutical Research, 33(1), pp.177–185.

 

He, Y. et al., 2016. In situ derivatization-ultrasound-assisted dispersive liquid–liquid microextraction for the determination of neurotransmitters in Parkinson’s rat brain microdialysates by ultra high performance liquid chromatography-tandem mass spectrometry. Journal of Chromatography A, 1458, pp.70–81.

 

Ortega, J., Meana, J.J. & Callado, L., 2016. In Vivo Brain Microdialysis of Monoamines. In R. Luján & F. Ciruela, eds. Receptor and Ion Channel Detection in the Brain. Neuromethods. Springer New York, pp. 415– 434. Available at: http://dx.doi.org/10.1007/978-1-4939-3064-7_25.

 

Qi, D. et al., 2016. Quantification of Dopamine in Brain Microdialysates with High-Performance Liquid Chromatography–Tandem Mass Spectrometry. Analytical Sciences, 32(4), pp.419–424.

Wang, F. et al., 2015. Sensitive Determination of Amantadine in Microdialysis Samples from Rat Plasma by HPLC with Fluorescence Detection. Journal of Liquid Chromatography & Related Technologies, 38(17), pp.1622–1628.

 

Keeler, G.D., Durdik, J.M. & Stenken, J.A., 2015a. Effects of delayed delivery of dexamethasone-21- phosphate via subcutaneous microdialysis implants on macrophage activation in rats. Acta Biomaterialia, 23, pp.27–37.

 

Visit our Publications page for a complete listing of CMA 120 publications.